An entirely new way of antagonizing a human nuclear receptor has been uncovered by scientists. They expect this to have significant impact in the world of drug research. Nuclear receptors are modulatory proteins that control numerous crucial bodily functions and thus play a key role in many pathologies. A new, potentially better method has been found to impact the function of these proteins. This opens an avenue whereby drugs could be developed with a decreased susceptibility to resistance.

Source: Scientists discover 'back door' of nuclear receptor


David Cottle

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