For the first time the protein Erbin has been shown to be an important brake that helps prevent pathological cardiac hypertrophy. Researchers showed that damage to this protein leads to excess growth of heart muscle, a decrease in function, and severe pathological growth of heart muscle. Their research has implications for breast cancer treatment, as Erbin interacts with the receptor Her2/ErBb2, which is overexpressed in approximately 30 percent of breast cancers.

Source: Protein's role revealed in preventing heart muscle growth leading to heart failure