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#448635
Wed 17 Jan 2018 03:40:PM
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Joined: Feb 2001
Posts: 381,904
Launch Director
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OP
Launch Director
Joined: Feb 2001
Posts: 381,904 |
An international team of researchers has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn's disease. Focusing on the immunomodulatory cytokine IL-23 they discovered that its pro-inflammatory activity, which underlies a wide range of inflammatory diseases, critically depends on structural activation of the cytokine by its receptor, IL-23R. Source: Scientists shed light on a key molecular mechanism of autoimmune and inflammatory diseases
David Cottle
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