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#456967
Mon 23 Apr 2018 06:33:PM
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Joined: Feb 2001
Posts: 381,903
Launch Director
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OP
Launch Director
Joined: Feb 2001
Posts: 381,903 |
Researchers tracked genomic alterations detected in patient samples during tumor cell evolution in culture, in patient-derived xenograft (PDX) mouse models from the cultures, as well as before and after treatment in patients. The team reports that tumor progression was often driven by cancer-promoting genes, known as oncogenes, on extrachromosomal pieces of DNA. Source: The role of 'extra' DNA in cancer evolution and therapy resistance
David Cottle
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