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#239155
Mon 04 Aug 2014 02:01:PM
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Joined: Feb 2001
Posts: 381,904
Launch Director
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OP
Launch Director
Joined: Feb 2001
Posts: 381,904 |
Despite improved therapy, only one out of every two adult patients survive acute myeloid leukemia (AML). The mean survival time for this disease, which predominantly occurs in the elderly, is less than a year for patients over 65 years. It is assumed that leukemic stem cells, which cannot be completely eliminated during treatment, are the origin of relapse. However, as has been recently discovered, these cells do have a weakness: the enzyme 5-lipoxygenase (5-LO) plays a significant role in the survival of leukaemic AML stem cells, it turns out.  Source: Weakness of leukemic stem cells discovered
David Cottle
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