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#503237
Fri 24 May 2019 12:16:PM
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Joined: Feb 2001
Posts: 381,904
Launch Director
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Launch Director
Joined: Feb 2001
Posts: 381,904 |
Infected tissue has a low concentration of oxygen. The body's standard immune mechanisms, which rely on oxygen, can then only function to a limited extent. How does the immune system nevertheless manage to control bacteria under such conditions? Researchers have discovered that fewer metabolites are produced in the citric acid cycle under hypoxic conditions, leading to a reduced rate of reproduction among bacteria in macrophages. Source: When macrophages are deprived of oxygen
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